Regulation Text
§ 61.53 Prohibition on operations during medical deficiency.
(a) Operations that require a medical certificate. Except as provided for in paragraph (b) of this section, no person who holds a medical certificate issued under part 67 of this chapter may act as pilot in command, or in any other capacity as a required pilot flight crewmember, while that person:
(1) Knows or has reason to know of any medical condition that would make the person unable to meet the requirements for the medical certificate necessary for the pilot operation; or
(2) Is taking medication or receiving other treatment for a medical condition that results in the person being unable to meet the requirements for the medical certificate necessary for the pilot operation.
(b) Operations that do not require a medical certificate. For operations provided for in § 61.23(b) of this part, a person shall not act as pilot in command, or in any other capacity as a required pilot flight crewmember, while that person knows or has reason to know of any medical condition that would make the person unable to operate the aircraft in a safe manner.
(c) Operations requiring a medical certificate or a U.S. driver's license. For operations provided for in § 61.23(c), a person must meet the provisions of—
(1) Paragraph (a) of this section if that person holds a medical certificate issued under part 67 of this chapter and does not hold a U.S. driver's license.
(2) Paragraph (b) of this section if that person holds a U.S. driver's license.
Docket 25910, 62 FR 16298, Apr. 4, 1997; Amdt. 61-110, 69 FR 44866, July 27, 2004; Amdt. 61-124, 74 FR 42550, Aug. 21, 2009
Research Notes
Research Notes
Section 61.53 is the self-grounding rule — it places a duty on the pilot, not just the AME, to assess fitness for flight. This is one of the most operationally significant rules in Part 61 because it applies even when a medical certificate is current and valid. A valid medical does not give the holder blanket clearance to fly regardless of current health status.
The "knows or has reason to know" standard: This is a subjective-plus-objective standard. It does not require a physician's diagnosis to trigger the prohibition. If a pilot subjectively knows something is wrong — a severe headache, dizziness, vision changes, a new medication with sedating effects — that is sufficient. "Reason to know" also captures situations where the symptoms are objectively obvious even if the pilot is in denial. NTSB accident reports have cited this provision in cases where pilots flew with conditions that would have prompted any reasonable person to ground themselves.
Medication prohibition: Paragraph (a)(2) specifically covers medications and treatments. The FAA maintains a list of allowed and prohibited medications at faa.gov/pilots/medical_certification/medications. Over-the-counter medications (antihistamines, cold medications, sleep aids) are among the most common triggers for this prohibition because pilots underestimate their sedating effects at altitude. The standard is functional impairment, not just prescription status.
BasicMed and driver's license operations: Paragraphs (b) and (c) address operations that don't require a traditional FAA medical — specifically BasicMed operations under § 61.23(b)–(c) and sport pilot operations using a driver's license. The standard for these operations is not the Part 67 medical standard but rather: can the person operate safely? This is a broader, self-assessed standard. Even without an AME in the loop, the pilot must still ground themselves when they know or have reason to know they cannot fly safely.
AOPA Medical Certification resources: AOPA maintains a Medical Certification section at aopa.org with guidance on specific conditions, medications, and how to navigate the AIMME (Aerospace Medical Monitoring and Evaluation) process for conditions that require special issuance.
Amendment History
AOA Notes
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CFI Commentary
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